Research Articles
The Bent Little Molecule in Your Liver: How a Single Enzyme Crafts Essential Biology
Discover how AKR1D1 enzyme bends steroids at right angles, enabling bile acid production and hormone regulation through unique structural mechanisms.
The pH Puzzle: How Acid Levels and Heavy Water Unlocked DHFR's Secrets
Discover how scientists used pH adjustments and deuterium isotope effects to unravel the mechanism of dihydrofolate reductase (DHFR), a crucial enzyme in folate metabolism.
The Molecular Machine: How Cyclodextrin Glycosyltransferase Builds Unique Rings from Starch
Explore the fascinating world of cyclodextrin glycosyltransferase (CGTase), a remarkable enzyme that transforms starch into cyclodextrins with applications in biotechnology, food production, and pharmaceuticals.
The Magnesium Key: How a Simple Ion Controls a Cellular Scissor
Unlocking the secrets of ribonuclease H reveals a delicate dance between enzyme and metal, where concentration is everything.
The Molecular Spring: How a Single Atom's Grip Powers a Cellular Bodyguard
Discover how the proximal ligand in peroxidase enzymes acts as a molecular spring, enabling cellular detoxification through precise atomic interactions.
The Gut Bacterium's Secret: How a Unique Enzyme Powers Your Health
Discover how the carboxyspermidine dehydrogenase enzyme in gut bacteria produces spermidine, a compound with remarkable health benefits including cellular health support and potential lifespan extension.
The Red Yeast's Hidden Gem: Unlocking the Secrets of Monascus purpureus Beta-Glucosidase
Exploring the biochemical properties and industrial applications of Monascus purpureus beta-glucosidase enzyme
The Resilient Heme Enzyme: How BsDyP Redefines Peroxidase Rules
Discover how BsDyP from Bacillus subtilis challenges peroxidase mechanisms by showing neither aspartate nor arginine are individually essential for its catalytic activity.